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Harnessing artificial intelligence to identify new drug combinations

Artificial intelligence (AI) has helped scientists propose a promising new drug combination for DIPG brain tumours. Prof Chris Jones, Director of the Brain Tumour Research Centre of Excellence at the Institute of Cancer Research (ICR), and Dr Fernando Carceller, Paediatric Neuro-Oncology Consultant at The Royal Marsden Hospital, tell us more.

How the latest treatments come about through clinical trials

New and innovative cancer treatments go through many steps to make their way from ‘bench to bedside’. Professor Pamela Kearns, Dr Sarah Al-Jilaihawi and Dr Jessica Douglas-Pugh from the University of Birmingham’s Cancer Research UK Clinical Trials Unit (CRCTU) explain more about this process.

The GRANS trial: Pioneering a novel treatment

Prof Robert Wynn, Consultant Paediatric Haematologist and Director of Bone Marrow Transplant at Royal Manchester Children’s Hospital, leads the GRANS clinical trial. He tells us how this innovative treatment is showing promising results for children with hard-to-treat leukaemia.

Molecular radiotherapy for children’s cancers

Molecular radiotherapy (MRT) is an evolving form of children’s cancer treatment. Dr Mark Gaze, Caroline Elmagrahi and Georgia Azzopardi, of University College London Hospitals NHS Foundation Trust, tell us more about what it is and what work is being done to develop its usage.

New online resource supporting children and their families

Charley Scott’s daughter was diagnosed with cancer as a two-year-old. She tells us about an accessible new information resource that she and her husband Jon have created to help other children and families, influenced by their own experiences.

Nutrition support options in childhood cancer

Sometimes, due to the effects of their cancer and its treatment, children may require extra support to get the nutrition they need. Breeana Gardiner, a specialist paediatric dietitian in haematology/oncology at Great Ormond Street Hospital, explains more.

Dealing with food cravings while on steroids

Hannah Longstaff's daughter, Matilda, was diagnosed with acute lymphoblastic leukaemia (ALL) in February 2022, aged three. She tells us how Matilda’s appetite increased after being put on steroids and about the support she has received.