Using a DNA molecule as a new and safer treatment for neuroblastoma
Professor Arturo Sala will test a promising new adult cancer treatment in neuroblastoma to find a kinder and more effective treatment options.
Helping immunotherapy work better for children with neuroblastoma by reprogramming the tumour environment
Professor James Arnold is creating a new type of immunotherapy that can fight solid tumours and make it easier for the immune system to help.
Evaluation and optimization of drug combinations that kill neuroblastoma cancer cells
Professor Karim Malik aims to test a new combination of drugs that can eliminate neuroblastoma cells.
Discovering new blood-based signals for monitoring brain tumours in children
Dr Alina Pandele at the University of Nottingham hopes to find fragments cancer cell genetic code in the blood which can help doctors know when ependymoma grows back.
Using an asthma medicine to harness the immune system and prevent childhood leukaemia from returning
Dr Sophie Kellaway at the University of Nottingham is investigating whether an asthma drug could help provide a new, targeted treatment for acute myeloid leukaemia.
Developing new cancer treatment testing models for children with leukaemia
Dr Katrina Lappin aims to create a cost effective and more accurate acute myeloid leukaemia model to test treatments on.
Reading critical changes in neuroblastoma’s genetic messages
Dr Jodie Bojko at the University of Bristol hopes to understand how genetic instructions are altered in neuroblastoma, and how this impacts the cancer.
Establishing a new comprehensive blood test to monitor rhabdomyosarcoma in children
Dr Supriti Ghosh at The Institute of Cancer Research hopes to learn more about how to use tiny fragments of DNA from the blood to monitor rhabdomyosarcoma.
Targeting a protein to treat acute myeloid leukaemia in children
Dr Karen Keeshan is researching to see if removing or blocking a specific protein involved in acute myeloid leukaemia can help make it easier to treat.