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Caroline Brown, Lead Complementary Therapist for Paediatrics, Teenagers and Young Adults at The Royal Marsden Hospital

Michelle Eldred’s daughter, Amelia, was diagnosed with bone cancer in 2017 on her seventh birthday. Here, Michelle tells us about a pioneering procedure which helped Amelia remain active after a leg amputation.

Artificial intelligence (AI) has helped scientists propose a promising new drug combination for DIPG brain tumours. Prof Chris Jones, Director of the Brain Tumour Research Centre of Excellence at the Institute of Cancer Research (ICR), and Dr Fernando Carceller, Paediatric Neuro-Oncology Consultant at The Royal Marsden Hospital, tell us more.

New and innovative cancer treatments go through many steps to make their way from ‘bench to bedside’. Professor Pamela Kearns, Dr Sarah Al-Jilaihawi and Dr Jessica Douglas-Pugh from the University of Birmingham’s Cancer Research UK Clinical Trials Unit (CRCTU) explain more about this process.

Prof Robert Wynn, Consultant Paediatric Haematologist and Director of Bone Marrow Transplant at Royal Manchester Children’s Hospital, leads the GRANS clinical trial. He tells us how this innovative treatment is showing promising results for children with hard-to-treat leukaemia.

Molecular radiotherapy (MRT) is an evolving form of children’s cancer treatment. Dr Mark Gaze, Caroline Elmagrahi and Georgia Azzopardi, of University College London Hospitals NHS Foundation Trust, tell us more about what it is and what work is being done to develop its usage.

Charley Scott’s daughter was diagnosed with cancer as a two-year-old. She tells us about an accessible new information resource that she and her husband Jon have created to help other children and families, influenced by their own experiences.

Children with cancer who also have learning difficulties and autism often have additional needs when it comes to their care. Jeanette Hawkins, CCLG’s Chief Nurse, tells us more about a project aiming to improve support for this group of patients.

Sometimes, due to the effects of their cancer and its treatment, children may require extra support to get the nutrition they need. Breeana Gardiner, a specialist paediatric dietitian in haematology/oncology at Great Ormond Street Hospital, explains more.

Exploring alterations in amino acid metabolism as novel therapeutic targets in paediatric glial tumours using advanced metabolomics methods