Making antibody immunotherapy for neuroblastoma safer
Investigating how antibody immunotherapy causes pain and nerve damage.
Precision medicines for paediatric acute myeloid leukaemia
Finding which MEK inhibitors work best for children with acute myeloid leukaemia.
Exploring ‘Junk DNA’ to find undiscovered causes of cancer
Using a new way to measure genetic variation in key sections of noncoding DNA.
What makes ependymoma in infants different?
Looking at molecular makeup and MRIs to characterise infant ependymoma.
A new protein targeted treatment for B-cell lymphoma
Assessing whether blocking a protein's activity could improve survival and reduce side effects.
A new targeted treatment for anaplastic large cell lymphoma
Stopping protein activity to stop anaplastic large cell lymphomas from growing.
Using existing drugs in a new way to treat high-risk acute lymphoblastic leukaemia
Finding drugs which target genes that drive high-risk acute lymphoblastic leukaemia.
Using synthetic antibodies to treat diffuse midline gliomas
Creating antibodies in the lab to treat diffuse midline gliomas and testing their effectiveness.
Investigating immune cells in sarcoma tumours
Finding why immunotherapy doesn't work for some children with sarcoma tumours.