Stopping drug resistant processes in T-cell acute lymphoblastic leukaemia
Developing a test to select patients who can be treated with a new medicine that prevents steroid resistance.
Blocking chemical reactions which keep ependymoma cells alive
Testing four medicines to see if they can shut down the metabolism of brain cancer cells grown in the lab
International clinical trial to test the use of dye during children’s cancer surgery
Testing whether a dye called Indocyanine Green (ICG) can help surgeons identify tumours and lymph nodes during surgery.
Delivering packaged drugs into paediatric brain tumours using ultrasound
Packing medicines into heat-sensitive liposomes to transport cancer treatments into the brain.
Identifying new drugs for the treatment of retinoblastoma
Testing new targeted drugs for retinoblastoma to find new treatment options.
Are regular blood and bone marrow tests helpful after childhood leukaemia?
Investigating the best follow up methods for childhood leukaemia to improve aftercare.
Liquid biopsies for rhabdomyosarcoma: A new way to improve rhabdomyosarcoma treatment
Looking for differences in newly diagnosed RMS patient samples to see if there are any that could be used to show whether treatments are working.
The glowing tumour trial for children with aggressive brain tumours
A clinical trial testing the use of the 'pink drink' dye in children with brain tumours.
Testing existing drugs in new combinations for high-risk neuroblastoma
Testing whether a combination of drugs could reduce the risk of relapse and limit side effects.