What factors affect the survival of children and young people with high-risk acute lymphoblastic leukaemia?
Finding out what makes ALL more high-risk, such as age of diagnosis or type of initial treatment.
Understanding why some childhood blood cancers are incurable
Using models to find out how high risk leukaemia cells grow and become resistant to treatment.
Creating a new immunotherapy approach to fight aggressive medulloblastoma
Finding a way to use immunotherapy against a high-risk type of childhood brain tumour.
Investigating clinical trial samples to predict how atypical teratoid rhabdoid tumours will respond to treatment
Looking at cancer samples to find markers that can predict how a child's cancer will respond to treatment.
Confirming bloodstream markers of children’s kidney cancer
Identifying markers that can be used for a non-invasive test to diagnose and monitor Wilms tumour.
How does teenage and young adult cancer treatment affect the risk of kidney disease?
This project aims to find out more about kidney damage in teenagers and young adults who have been treated for cancer. Dr Nicola Hughes wants to know what puts young people with cancer at risk of kidney damage, and to create helpful information for patients and their families.
What are young people and their families’ experiences of melanoma?
This project will investigate how young people and their families experience skin cancer. Dr Wendy McInally hopes to further develop the teenage and young adult cancer service, and create information that will help young people with skin cancer and their families.
Repurposing alcohol-abuse medicines to treat brain tumours
Understanding how a repurposed drug attacks and kills diffuse midline glioma cells.
Stopping drug resistant processes in T-cell acute lymphoblastic leukaemia
Developing a test to select patients who can be treated with a new medicine that prevents steroid resistance.