‘ALL’ about metabolism: repurposing drugs for acute lymphoblastic leukaemia
Examining whether a group of drugs called gliflozins could be used to treat T-ALL
We have been funding expert research since 2016, aiming to ensure that every child and young person has a safe and effective treatment for their cancer, and that they can live long and happy lives post-treatment.
Examining whether a group of drugs called gliflozins could be used to treat T-ALL
Developing and delivering small molecule drug and immunotherapy combinations for MYC-driven medulloblastoma: Efficacy, evolution and exploitation.
Single-cell transcriptomics linked to lineage tracing to interrogate the role of intra-tumour heterogeneity in shaping therapeutic susceptibility and resistance in paediatric cancer
Development of a multi-factorial prognostic model to optimise treatment decision making and outcomes in paediatric low-grade glioma
Defining the molecular landscape of paediatric and adolescent acute leukaemia in Tanzania
Towards chemotherapy-free treatment of paediatric post-transplant lymphoproliferative disorders
Living with treatment-related hearing loss: Experiences of survivors of childhood brain cancer
Towards a new therapy against childhood brain cancer: How does the Zika virus kill aggressive brain tumour cells?
Evaluating the efficacy of Enhancer of Zeste Homolog 2 (EZH2) inhibitors in combination with anti-GD2/isotretinoin for the treatment of high-risk neuroblastoma: a pre-clinical study