Understanding the evolution of neuroblastoma to improve treatment
Single-cell transcriptomics linked to lineage tracing to interrogate the role of intra-tumour heterogeneity in shaping therapeutic susceptibility and resistance in paediatric cancer
Single-cell transcriptomics linked to lineage tracing to interrogate the role of intra-tumour heterogeneity in shaping therapeutic susceptibility and resistance in paediatric cancer
Charley Scott’s daughter was diagnosed with cancer as a two-year-old. She tells us about an accessible new information resource that she and her husband Jon have created to help other children and families, influenced by their own experiences.
New and innovative cancer treatments go through many steps to make their way from ‘bench to bedside’. Professor Pamela Kearns, Dr Sarah Al-Jilaihawi and Dr Jessica Douglas-Pugh from the University of Birmingham’s Cancer Research UK Clinical Trials Unit (CRCTU) explain more about this process.
Caroline Brown, Lead Complementary Therapist for Paediatrics, Teenagers and Young Adults at The Royal Marsden Hospital
Pritesh Patel, Senior Specialist Pharmacist in Paediatric Cancer at Great Ormond Street Hospital for Children and CCLG member
Prof Robert Wynn, Consultant Paediatric Haematologist and Director of Bone Marrow Transplant at Royal Manchester Children’s Hospital, leads the GRANS clinical trial. He tells us how this innovative treatment is showing promising results for children with hard-to-treat leukaemia.
Michelle Eldred’s daughter, Amelia, was diagnosed with bone cancer in 2017 on her seventh birthday. Here, Michelle tells us about a pioneering procedure which helped Amelia remain active after a leg amputation.
Gareth Veal, Professor of Cancer Pharmacology at the Newcastle University Cancer Centre, leads a team helping doctors to personalise treatments through an innovative process called ‘therapeutic drug monitoring’. Here, he tells us more about his work.
Hannah Longstaff's daughter, Matilda, was diagnosed with acute lymphoblastic leukaemia (ALL) in February 2022, aged three. She tells us how Matilda’s appetite increased after being put on steroids and about the support she has received.