Delivering packaged drugs into paediatric brain tumours using ultrasound
Packing medicines into heat-sensitive liposomes to transport cancer treatments into the brain.
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What are the origins of liver cancer in children and why does treatment sometimes fail?
Understanding how hepatocellular carcinoma develops and what role the immune system plays.
Creating a new combination treatment for children's brain tumours
Repurposing medicines to support a new type of immunotherapy for brain tumours.
Developing novel drugs for medulloblastoma
This research focuses on the development of novel drugs for the treatment of childhood brain tumours.
Are regular blood and bone marrow tests helpful after childhood leukaemia?
Investigating the best follow up methods for childhood leukaemia to improve aftercare.
How do leukaemia stem cells talk to the immune system in juvenile myelomonocytic leukaemia?
Find out how JMML cells are able to switch off the immune system, causing relapse.
Why do some leukaemia patients have long-term problems with learning and memory
Finding a way to identify patients at risk of brain related side effects from leukaemia treatment, and gathering data to inform future treatment options.
A new protein targeted treatment for B-cell lymphoma
Assessing whether blocking a protein's activity could improve survival and reduce side effects.
Predicting high-risk rhabdomyosarcoma at diagnosis to improve outcomes
Assessing rhabdomyosarcoma risk prediction markers based on the biological conditions in the tumour, like low oxygen levels, few blood vessels, and genetics.