The projects have been funded through the LPT’s New Ideas grant scheme, with CCLG’s expert insights and resources helping to identify the most impactful proposals. The scheme supports early-stage, creative ideas that have the potential to transform the treatment and care of children and young people (CYP) with cancer.
As part of CCLG’s partnership with the LPT, it will support the researchers throughout their projects. Early-phase research is vital: it lays the groundwork for breakthroughs in understanding CYP cancer and developing new treatments. CCLG’s support will help LPT-funded researchers explore bold ideas and to help drive progress in treatment and care.
Phil Brace with Wendy Tarplee-Morris, one of the founders of the LPT.
Phil Brace, CEO of the LPT, said: “We are proud to offer funding for researchers at the earliest stages of their research. This funding gives researchers the chance to explore bold new ideas – like Prof Rylie Green, who is developing a new way of treating childhood brain tumours, or Prof John Anderson, who is creating advanced immunotherapies that can ‘rest and recover’ while fighting cancer.
Through initiatives like the New Ideas scheme, we are ensuring that our amazing supporters will have the biggest impact in shaping a brighter future for children with cancer.
The 2025 New Ideas projects will explore:
- A new approach to deliver chemotherapy directly into brain tumours, with Prof Rylie Green at Imperial College London
- Finding kinder drugs in genetically matched cell models for childhood leukaemia, with Prof Alex Thompson at the University of Nottingham
- Developing a new drug for the treatment of ALT-positive cancers, with Dr Jon Elkins at the University of Oxford
- Making CAR-T cells that can rest to improve their cancer-fighting ability, with Prof John Anderson at University College London Great Ormond Street Institute of Child Health
- Fighting brain cancer with CAR-T cells: Targeting zombie cells to improve therapy, with Dr Ashley Vardon at the University of Birmingham