Creating the West Midlands Childhood Cancer Clinical Cohort
Gathering data to uncover how childhood cancer and its treatment impacts survivors long-term quality of life.
What are the effects of radiation and chemotherapy on children’s developing brains?
Looking at the differences between healthy brain cells before and after treatment to uncover the mechanisms behind brain-related late effects.
Why do some leukaemia patients have long-term problems with learning and memory
Finding a way to identify patients at risk of brain related side effects from leukaemia treatment, and gathering data to inform future treatment options.
Why does neurodegeneration occur in Langerhans cell histiocytosis?
Discovering what causes nerve cells to stop working and die years after a Langerhans cell histiocytosis diagnosis.
Investigating why some children get leukaemia after treatment for other cancers
Looking at the early stages of leukaemia that develops after treatment for other cancers to find out what changes occur and how to fight it.
Protecting young hearts from chemotherapy-related heart problems
Investigating whether giving a medicine before doxorubicin cancer treatment could prevent heart damage.
How does teenage and young adult cancer treatment affect the risk of kidney disease?
This project aims to find out more about kidney damage in teenagers and young adults who have been treated for cancer. Dr Nicola Hughes wants to know what puts young people with cancer at risk of kidney damage, and to create helpful information for patients and their families.
Can radiotherapy near the spleen lead to severe infections later in life?
Looking into whether survivors of childhood cancer are at risk of severe infections.
Improving treatment decisions and outcomes in low grade glioma
Development of a multi-factorial prognostic model to optimise treatment decision making and outcomes in paediatric low-grade glioma