International clinical trial to test the use of dye during children’s cancer surgery
Testing whether a dye called Indocyanine Green (ICG) can help surgeons identify tumours and lymph nodes during surgery.
Making antibody immunotherapy for neuroblastoma safer
Investigating how antibody immunotherapy causes pain and nerve damage.
Precision medicines for paediatric acute myeloid leukaemia
Finding which MEK inhibitors work best for children with acute myeloid leukaemia.
Exploring ‘Junk DNA’ to find undiscovered causes of cancer
Using a new way to measure genetic variation in key sections of noncoding DNA.
A new protein targeted treatment for B-cell lymphoma
Assessing whether blocking a protein's activity could improve survival and reduce side effects.
Investigating immune cells in sarcoma tumours
Finding why immunotherapy doesn't work for some children with sarcoma tumours.
Using existing drugs in a new way to treat high-risk acute lymphoblastic leukaemia
Finding drugs which target genes that drive high-risk acute lymphoblastic leukaemia.
Targeting proteins to fight acute myeloid leukaemia
Understanding how proteins act inside acute myeloid leukaemia cells, to find new drug targets.
Using genetics to understand why acute myeloid leukaemia cells don’t respond to treatment
Looking at the genetics of bone marrow samples to see which genes affect resistance to treatment.