Our research projects

Professor Clare Davies and Dr Susanne Gatz explore whether PRMT5 inhibitors could be an effective and kinder treatment for Ewing sarcoma.

Professor Plevin and Dr Margaret Cunningham will investigate an enzyme that might play a role in osteosarcoma development, and see whether this could form the basis of a new type of treatment.

Developing a test that can measure the amount of chemotherapy-resistant leukaemia cells in patient's blood samples. This would provide the foundations for future research.

Understanding how a protein affects the growth and development of lymphoma cells in order to build the foundations for safer and more effective treatments.

Learning more about leukaemia cells in order to design targeted treatments that can increase survivorship and quality of life.

Ependymoma comes back after treatment around half of the time, because some cancer cells are still alive. If doctors could identify these cells and diagnose relapsed ependymoma sooner, children could start treatment earlier.

Dr Jess Morgan at Leeds Children’s Hospital and Dr Gemma Bryan at University of Surrey hope to understand more about how hospitals are offering chemotherapy that needs to be given as infusions over a number of days.

Looking at how a process called 'cut-and-run' leads to genetic errors, and how those errors could be prevented in order to prevent relapse in childhood leukaemia.

Developing a living systematic review of studies into new treatments for relapsed and refractory rhabdomyosarcoma.