Activating a protein to make immunotherapy more effective for neuroblastoma
Professor Aymen Al-Shamkhani at the University of Southampton hopes to test a way to recruit immune cells into neuroblastoma tumours, making immunotherapy more effective.
We have been funding expert research since 2016, aiming to ensure that every child and young person has a safe and effective treatment for their cancer, and that they can live long and happy lives post-treatment.
Professor Aymen Al-Shamkhani at the University of Southampton hopes to test a way to recruit immune cells into neuroblastoma tumours, making immunotherapy more effective.
Professors Suzanne Turner, Anna Philpott and Aditi Vedi at the University of Cambridge will test a new combination treatment for neuroblastoma that could make current immunotherapies more effective.
Professor Karim Malik aims to test a new combination of drugs that can eliminate neuroblastoma cells.
Professor Arturo Sala will test a promising new adult cancer treatment in neuroblastoma to find a kinder and more effective treatment options.
Professor James Arnold is creating a new type of immunotherapy that can fight solid tumours and make it easier for the immune system to help.
Dr Jodie Bojko at the University of Bristol hopes to understand how genetic instructions are altered in neuroblastoma, and how this impacts the cancer.
Dr Lizzie Tucker will assess a new type of treatment to fight ALK-driven childhood cancers like neuroblastoma.
Professor Karim Malik and Dr Jodie Bojko are testing drugs that can prevent cancer cells from making growth-promoting proteins.
Dr Daniel Williamson’s expert team will find the best malignant rhabdoid tumour models to test exciting new treatments.