We have been funding expert research since 2016, aiming to ensure that every child and young person has a safe and effective treatment for their cancer, and that they can live long and happy lives post-treatment.
Dr Jess Morgan at the University of York will review the latest experimental treatments for hard-to-treat neuroblastoma to help with decision-making.
Studying how neuroblastoma cells and immune cells interact over time to see how the cancer adapts to treatment.
Looking at what extra pieces of chromosomes do in neuroblastoma and how these work with the MYCN protein to convert healthy cells into cancer cells.
Modifying current immunotherapy so that it doesn't cause damage to nerve cells and instead targets three molecules to help kill neuroblastoma cells more effectively.
Finding out which changes to how DNA is read in neuroblastoma can give doctors more information about the cancer, and investigating whether these changes could be stopped through medicines.
Investigating how cancer cells can keep dividing and why this makes it harder to treat.
Using anti-depressants to prevent the body's immune system from fighting immunotherapy treatments.
Testing whether a combination of drugs could reduce the risk of relapse and limit side effects.
This research focuses on the development of novel drugs for the treatment of childhood brain tumours.
