How do leukaemia stem cells talk to the immune system in juvenile myelomonocytic leukaemia?
Find out how JMML cells are able to switch off the immune system, causing relapse.
Blocking processes which keep leukaemia cells alive
Investigating the possibility of combining a medicine that blocks the process with a medicine that triggers a cell's defensive response to treat ALL.
Stopping drug resistant processes in T-cell acute lymphoblastic leukaemia
Developing a test to select patients who can be treated with a new medicine that prevents steroid resistance.
Are regular blood and bone marrow tests helpful after childhood leukaemia?
Investigating the best follow up methods for childhood leukaemia to improve aftercare.
Precision medicines for paediatric acute myeloid leukaemia
Finding which MEK inhibitors work best for children with acute myeloid leukaemia.
Using existing drugs in a new way to treat high-risk acute lymphoblastic leukaemia
Finding drugs which target genes that drive high-risk acute lymphoblastic leukaemia.
Targeting proteins to fight acute myeloid leukaemia
Understanding how proteins act inside acute myeloid leukaemia cells, to find new drug targets.
Using genetics to understand why acute myeloid leukaemia cells don’t respond to treatment
Looking at the genetics of bone marrow samples to see which genes affect resistance to treatment.
A better way of delivering drugs for acute myeloid leukaemia
Testing nanoparticles as a way of getting drugs where they are needed for acute myeloid leukaemia.