Rewriting cancer cell messages to slow down tumour growth
Testing medicines that can correct the genetic messages that help cancer cells grow out of control.
Determining the best approach to treat children with relapsed anaplastic large cell lymphoma
Looking at why ALCL sometimes relapses with a new targeted treatment, and understanding how to optimise this treatment approach.
Making Wilms tumour cells go green
Developing a new dye to make kidney cancer surgery safer and more effective.
UMBRELLA PLUS - molecular-driven treatments for kidney cancer
Improving genetic testing for children with kidney cancers like Wilms tumour and finding a way to improve diagnosis and relapse monitoring.
Could a medicine called ONC-201 help treat children with T-cell acute lymphoblastic leukaemia?
Looking at whether a pre-existing drug could be an effective and safe treatment due to its ability to target cancer cells directly.
What role do small pieces of genetic code play in germ cell tumours?
Investigating how different levels short non-coding RNAs affect germ cell tumour cells, and testing whether medicines altering these levels could be a potential treatment.
Could ‘prehabilitation’ help prepare children with cancer for a stem cell transplant?
Investigating whether diet or lifestyle changes could help children cope with bone marrow transplants better.
Exploring new targeted therapy options for acute myeloid leukaemia in babies
Looking for repurposed treatments that can fight leukaemia cells in very young children.
A new immunotherapy treatment for paediatric high-grade glioma
Creating a new immunotherapy that will attacks collagen in cancer cells, and testing whether it is effective in model systems to make it the best it can be.