Scientist working with blood samples

Current projects using the CCLG Tissue Bank

The following projects are currently using the CCLG Tissue Bank 

 

Study number Study title Co-Investigator Institution
2016 BS 04 Detection of novel autoantibodies in children with Opsoclonus Myoclonus Syndrome Dr Bethan Lang University of Oxford, Dept of Neurosciences
2016 BS 03 Genetic profiling of high risk neuroblastomas to provide predictive and prognostic biomarkers for current and future targeted therapies: A SIOPEN retrospective study. Prof Debbie Tweddle Northern Institute for Cancer Research, Newcastle University
2016 BS 02 A genome wide comparison of paired diagnostic and relapsed neuroblastomas Prof Debbie Tweddle Northern Institute for Cancer Research, Newcastle University
2016 BS 01 Molecular Characterisation of Adamantinomatous Craniopharyngioma Dr J-P Martinez-Barbera UCL, Institute of Child Health
2015 BS 09 Prospective targeted next generation sequencing (NGS) for the detection of genomic alterations in newly diagnosed and relapsed paediatric solid tumour patients: a feasibility study Dr Louis Chesler Institute of Cancer Research, Sutton, Surrey
2015 BS 08 Examination of genetic/genomic events underlying the pathogenesis of Anaplastic Large Cell Lymphoma Dr Suzanne Turner Cambridge University
2015 BS 07 Determining the clonality of neuroblastoma tumours Dr Elizabeth Calton Institute of Cancer Research, Sutton, Surrey
2015 BS 06 Application of high resolution gene expression and genomic platforms to the analysis of paediatric Hodgkin lymphoma using microdissected FFPE samples Dr Vikki Rand Northern Institute for Cancer Research, Newcastle University
2015 BS 05 Metabolite profiles as a means of identifying genetic subtypes of medulloblastoma Prof Andrew Peet School of Cancer Sciences, University of Birmingham
2015 BS 04 Prognostic impact of ALK mutations and amplification in patients with high-risk neuroblastoma - a SIOPEN study Prof Debbie Tweddle Northern Institute for Cancer Research, Newcastle University
2015 BS 03 Identification of novel gene networks responsible for the development of glioneural tumours Dr Tom Jacques UCL, Institute of Child Health
2015 BS 02 Molecular insights into ubiquitin remodelling factor p97NCP in DNA damage response and genomic stability Dr Kristijan Ramadan CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford
2015 BS 01 BIOMarkers of Ependymoma in Children and Adolescents (BIOMECA) - integrated biological study within SIOP Ependymoma II trial organised by European Ependymoma Biology Consortium Prof Richard Grundy University of Nottingham, Children's Brain Tumour Research Centre
2014 BS 11 Detection of circulating tumour DNA (ctDNA) as a biomarker for childhood solid tumours Dr Tom Jacques UCL, Institute of Child Health
2014 BS 10 The detection of genomic alterations by next generation sequencing (NGS) technology in paediatric solid tumours Dr Sally George Institue of Cancer Research, Sutton, Surrey
2014 BS 09 Analysis of miRNA processing genes in DICER1-related childhood tumours Dr Marc Tischkowitz University of Cambridge
2014 BS 08 Investigating the immunosuppressive microenvironment within neuroblastoma tumours Dr Francis Mussai School of Cancer Sciences, University of Birmingham
2014 BS 07 Investigating the role of XRN1 in osteosarcoma Dr Sarah Newbury University of Sussex
2014 BS 05 PILOT STUDY: Investigating clonal evolution in hepatoblastoma Dr John Anderson UCL, Institute of Child Health
2014 BS 03 Genomic analysis of paeditric anaplastic large cell lymphoma (ALCL) Dr Vasiliki Leventaki St Jude Children's Research Hospital, Memphis, USA
2014 BS 02 Improved outcome prediction of children with neuroblastoma using an integrated m/miRNA and DNA methylation signature Dr Frank Speleman Centre for Medical Genetics, Ghent, Belgium
2014 BS 01 SNPs in cardiac ABC transporter genes as predictors of anthracycline induced cardiomyopathy in childhood cancer Dr Stephen Lowis University Hospitals of Bristol
2013 BS 03 Role of c-Myc in choroid plexus tumours Dr Ashirwad Merve St Barts, Department of Neurosciences
2013 BS 02 Improving Population Outcomes for Renal Tumours of Childhood (IMPORT) Prof Kathy Pritchard-Jones UCL, Institute of Child Health
2012 BS 08 Characterisation of childhood B-cell non-Hodgkin's lymphoma (B-NHL) Dr Vikki Rand Northern Institute for Cancer Research, Newcastle University
2012 BS 07 Discovery and prioritisation of frequently mutated genes in tumour cells of paediatric Hodgkin's lymphoma through whole genome amplification and whole exome sequencing Dr Paul Murray University of Birmingham, School of Cancer Sciences
2012 BS 06 Molecular classification of retinoblastoma Dr Carmel McConville University of Birmingham, School of Cancer Sciences
2012 BS 05 Molecular biological characterisation of malignant rhabdoid tumours Dr Dan Williamson Northern Institute for Cancer Research, Newcastle University
2012 BS 01 Identifying genetic risk factors for cisplatin-induced ototoxicity in childhood cancer patients Prof Barry Pizer Institute of Translational Medicine, University of Liverpool
2011 BS 05 Pharmacokinetcs and pharmacogenetics of anticancer drugs in children Dr Gareth Veal Northern Institute for Cancer Research, Newcastle University
2011 BS 03 A role for NK cells in progression and regression of neuroblastoma Dr Clair Gardiner Trinity College, Dublin, Ireland
2010 BS 04 GENEWING, genome wide association study for susceptibility genes in Ewing sarcoma Dr Olivier Delattre Institut Curie, France
2010 BS 03 Heterogeneity of ESFT; drug resistance, telomerase and the cancer initiating hypothesis Prof Sue Burchill Leeds, Institute of Molecular Medicine
2008 BS 12 A feasibility study of real time biological characterisation of medulloblastoma Prof Steve Clifford Northern Institute for Cancer Research, Newcastle University
2008 BS 10 Molecular pathogenesis of choroid plexus tumours Dr Vincent Ruland Institute of Neuropathology, University Hospital Muenster
2007 BS 05 CYP3A5 genotype as a potential risk factor for the development of ifosfamide nephrotoxixity in children Dr Gareth Veal Northern Institute for Cancer Research, Newcastle University
2007 BS 04 The molecular basis of childhood medulloblastoma: from genomics to improved theories. Prof Steve Clifford Northern Institute for Cancer Research, Newcastle University
2007 BS 02 Detection of minimal or residual disease in ALCL Dr Amos Burke Cambridge University Hospitals NHS Foundation Trust
2006 BS 06 Cooperative research strategy for paediatric high grade glioma: comprehensive mapping of gene expression and genomic gains and losses in paediatric high-grade glioma Prof Richard Grundy University of Nottingham, Children's Brain Tumour Research Centre
2006 BS 05 Comprehensive molecular analysis of tumour samples from patients entered onto previous and current European rhabdomyosarcoma clinical trials. Dr Janet Shipley Institute of Cancer Research, Sutton, Surrey
2005 BS 04 Dissecting the biology of DS-AMKL Dr Paresh Vyas Weatherall Institute of Molecular Medicine, Oxford
2004 BS 05 Factors Associated with Childhood Tumours (FACT) Study Dr Nazneen Rahman Institute of Cancer Research, Section of Genetics and Epidemiology
2004 BS 01 Genome-wide molecular characterisation of supratentorial PNET (sPNET) as part of infant brain studies, PNET III and HART studies Prof Richard Grundy University of Nottingham, Children's Brain Tumour Research Centre
2003 BS 08 Influence of Epstein-Barr virus status on outcome in paediatric Hodgkin lymphoma Prof Richard Grundy University of Nottingham, Children's Brain Tumour Research Centre
2003 BS 07 High-risk neuroblastoma study 1 of SIOP Europe: detection of minimal residual disease Prof Sue Burchill Leeds, Institute of Molecular Medicine
2003 BS 03 Comprehensive molecular profiling of Wilms tumours treated in the SIOP WT 2001 clinical trial Prof Kathy Pritchard-Jones UCL, Institute of Child Health
2002 BS 03 Study of gene expression of paediatric malignant germ cell tumours using micro-arrays Dr James Nicholson Cambridge University
2000 BS 06C A molecular cytogenetic and molecular genetic study of paediatric ependymoma Prof Richard Grundy University of Nottingham, Children's Brain Tumour Research Centre
1998 BS 07 Genetic alterations in relapsed Wilms tumours Prof Kathy Pritchard-Jones UCL, Institute of Child Health
1997 BS 02 Characterisation of Ewing's sarcoma, pNET, rhabdomyosarcoma and neuroblastoma using reverse transcriptase polymerase chain reaction Prof Sue Burchill Leeds, Institute of Molecular Medicine